Nemo Equipment Persist Womens 45L vs. Hyperlite Mountain Gear Southwest

Two carry-on travel backpacks, compared spec for spec.

Nemo Equipment Persist Womens 45L

Front facing view of the Nemo Equipment Persist Womens 45L
Capacity45 L
Weight1.6 kg
Dimensions64×34×33 cm
Airline fit1%
Price$260

Feature by feature

Nemo Equipment Persist Womens 45LFeatureHyperlite Mountain Gear Southwest
Storage
5 Compression 5
None Expanded Capacity None
0 Opening 2
top Passport
N Passthrough N
Carry
Y Backpack Y
Y Hip Belt Y
Y Sternum Strap removable
Inside
N Laptop N
8 Main Compartments 1
N Organizer N
Outside
× Hard Shell ×
N Rain-fly N
2, side Water Bottle Holder 2, side
Y Water Resistant Y
Material
300D/900D ripstop weaveDyneema® 200-denier

Hyperlite Mountain Gear Southwest

Front facing view of the Hyperlite Mountain Gear Southwest
Capacity40 L
Weight0.8 kg
Dimensions70×28×17 cm
Airline fit12%
Price$380

Key differences between the Nemo Equipment Persist Womens 45L and Hyperlite Mountain Gear Southwest

Both have: compression straps, backpack straps, hip belt, water bottle pockets, water resistant.

Which airlines take each bag as a carry-on

We checked both bags against the carry-on size limits of 189 airlines. 1 accept both. 0 accept only the Nemo Equipment Persist Womens 45L, and 22 accept only the Hyperlite Mountain Gear Southwest.

Only the Hyperlite Mountain Gear Southwest fits

Adria Airways, Air Europa, Air Koryo, Air New Zealand, Air Tahiti Nui, Azul Linhas, China Southern, Cubana de Aviacion, Hainan Airlines, Korean Air, Philippine Airlines, Royal Air Morocco, Saudi Arabian Airlines, Sichuan Airlines, SilkAir, Silver Airways, Singapore Airlines, SpiceJet, TAAG Angola, TAM Airlines, Ural Airlines, Virgin America.

Nemo Equipment Persist Womens 45L vs. Hyperlite Mountain Gear Southwest: which should you pack?

The Nemo Equipment Persist Womens 45L carries 5L more than the Hyperlite Mountain Gear Southwest (45L vs. 40L), while the Hyperlite Mountain Gear Southwest is the lighter pack at 0.8kg (vs. 1.6kg). For carry-on flexibility, the Hyperlite Mountain Gear Southwest fits 12% of the airlines we track — the higher of the two. If you prioritise packing volume, choose the Nemo Equipment Persist Womens 45L; if you want to travel lighter, the Hyperlite Mountain Gear Southwest is the better call.